Episode 89 - Alessandra Edwards: High-Performance & Well-Being Coach, Genetic Strategy Mentor & Author

Jane Anderson High Performance and Well-Being Coach, Personalised Genetic Strateg

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Jane Anderson's Show with Alessandra Edwards

Most high performers don't have a motivation problem. They have an information problem.

That's the core message from Alessandra Edwards, a clinical nutritionist and epigenetic coach who has spent more than 16 years helping executives, founders, and business owners across Australia, New Zealand, Europe, and the US understand their own biology instead of fighting it.

In a conversation on Apple Podcast, Alessandra shared the framework she now uses with high-level leaders: the DNA Performance Framework. It's built on a simple premise: the generic advice to "sleep more, eat clean, exercise daily" fails because it ignores that everyone's biology runs on a different operating system.

This article breaks down what that framework actually looks like, why exhaustion in high performers is often genetic rather than a discipline issue, and what Alessandra tells clients to do about it, starting with taking things away, not adding more.

Who Is Alessandra Edwards?

Alessandra Edwards is a high-performance and well-being coach, personalised genetic strategy mentor, trainer, and author who works at the intersection of clinical nutrition and epigenetics. She holds first-class degrees in health science, alongside professional qualifications in genomic wellness, herbal medicine, neurolinguistic programming, yoga, and meditation instruction.

Her client base spans thought leaders, executives, founders, and business owners across four continents. Rather than offering one-size-fits-all wellness advice, she helps clients map their genetic "operating manual" before building a personalised routine around it.

What sets her apart isn't just the credentials. It's that she's lived the problem she now helps others solve.

A Personal Story Behind the Framework

Alessandra grew up in a French household in Italy, in what she describes candidly as one of the least health-focused environments she's encountered. Exercise and wellness weren't valued growing up, and after losing her father at a young age, she experienced significant mental health challenges in her twenties, including a diagnosis of major depression.

Conventional medicine helped her function again, but it didn't fully restore the sense of vitality she was looking for. That gap is what eventually pushed her from a corporate marketing and public-sector career back into study, first in traditional medicine, then into a second degree in health science focused on genetics.

It was during that deeper study that she recognised a pattern in herself: she is what she calls a "Supernova," a genetic profile prone to bursts of high productivity followed by crashes in energy and mood. Understanding this reframed what she'd previously been told was simply "burnout" into something far more specific and manageable.

What Is the DNA Performance Framework?

The DNA Performance Framework is Alessandra's model for translating genetics into practical daily decisions. Instead of treating high performance and well-being as separate goals, the framework treats them as two sides of the same equation, productivity and capability on one side, vitality, resilience, and relationships on the other.

In practice, many high achievers are strong on the first side and quietly failing on the second: productive, successful, and exhausted, disconnected, or irritable underneath it.

The framework maps four "signatures" for each client:

  • Energy signature: how your energy rises and falls throughout the day

  • Stress signature: your baseline resilience and how you process pressure

  • Athletic signature: the type of exercise most likely to restore your energy

  • Diet signature: the foods and eating patterns that work with your biology, not against it

Understanding Your Energy Signature

Within energy signatures, Alessandra identifies genetically-influenced patterns for the best times to wake, sleep, exercise, do focused cognitive work, and hold conversations, because different neurochemicals dominate at different points in the day.

Three energy types came up directly in the conversation:

  • Supernova: goes hard, all day, every day, with strong bursts of drive but limited endurance. Needs scheduled full breaks (Alessandra recommends a full week off periodically, not a packed multi-country trip) rather than constant low-grade rest.

  • Electric Star: sustains high, constant output. Benefits from very short recovery "pit stops" throughout the day, brief breathing breaks or stepping away from the screen, rather than long breaks.

  • Shooting Star: energy that spikes and dips more sharply. Tends to do better eating small protein-rich snacks every couple of hours and building in more regular physical movement.

The point isn't to label yourself. It's to stop applying someone else's routine to your own biology.

For a Supernova, for example, the advice isn't "push through and rest when you crash." It's the opposite, schedule genuine recovery before the crash happens, because the pattern of intense output followed by a dip is already baked into the biology. For an Electric Star, the fix is smaller and more frequent: a handful of seconds spent breathing or looking away from a screen, repeated throughout the day, rather than waiting for a single big break to fix everything. Neither approach works well applied to the wrong type, which is exactly why generic productivity or wellness advice so often fails people who've genuinely tried to follow it.

Why High Performers Experience Chronic Exhaustion

Ask Alessandra what the single most common issue is across the executives, founders, and thought leaders she works with, and the answer is immediate: exhaustion.

But not the kind that resolves with a good night's sleep.

This is exhaustion people feel in their bones and in their brain, the kind that starts to affect memory and focus, not just energy levels. Clients describe it as a mental "fog": repeating themselves, losing their train of thought mid-session, or momentarily forgetting details they'd normally know well.

Why Sleep Disruption Isn't Solved by "More Sleep"

The second major pattern is sleep, though not in the way most people expect. Falling asleep usually isn't the issue. Waking in the night, ruminating, and struggling to get back to sleep is far more common.

That disrupted sleep creates a cycle: a rough night leads to reaching for quick fixes the next day, whether that's sugar or excess caffeine. Because caffeine clearance is partly genetically determined, some people process it quickly, while others stay "wired" for two to three days after a single dose, disrupting sleep again and repeating the pattern.

The Hidden Link Between Perimenopause and Confidence

A pattern that tends to surface later in coaching conversations, and one Alessandra says carries real stigma, is a loss of confidence tied to hormonal change, particularly in middle-aged women going through perimenopause.

This often shows up as more than typical imposter syndrome. Clients describe losing the drive and hunger they once had, questioning their own identity, and in some cases withdrawing from opportunities altogether, a pattern Alessandra has seen especially among women working in male-dominated industries like finance and banking.

Her point is direct: this isn't a mindset failure to be fixed with more affirmations or more meditation. A genuine oestrogen deficiency, for example, can lower serotonin and dopamine and slow metabolic rate: biochemical shifts that meditation alone won't reverse. Naming the actual cause is what allows for an actual solution.

Why "Doing Less" Beats "Doing More"

Perhaps the most counterintuitive part of Alessandra's approach is that most clients don't need another supplement, another exercise plan, or another wellness habit stacked on top of what they're already doing.

She describes new clients arriving with a life that's like an overfilled canvas, a habit from a naturopath here, advice from a podcast there, a recommendation from a health coach layered on top, with no space left, and a persistent undercurrent of guilt about not doing enough.

The Clay, Not Canvas, Approach to Behaviour Change

Her reframe: think of the client as a piece of clay, not a canvas. The work isn't adding another layer, it's taking things away, one small change at a time, then observing what settles before making the next adjustment.

This mirrors a broader principle in behaviour change, small, sequential 1% adjustments tend to be more sustainable and far less overwhelming than an all-at-once overhaul, particularly for business owners already stretched across running a company, managing a team, and often a family as well.

Building Authority: Why Alessandra Recommends Writing a Book

Asked what advice she'd give her younger self starting out in practice, Alessandra's answer wasn't about clinical technique. It was about business positioning: get over yourself, and get a book written sooner rather than later.

Her reasoning, echoed by peers who've written multiple books, is that authoring a book is one of the most effective ways to shift from being seen as a consultant to being recognised as a thought leader, which in turn supports higher rates and deeper client conversations, since prospective clients arrive already understanding the practitioner's core ideas.

Alessandra is currently finishing her own book, covering the energy-signature component of the DNA Performance Framework, with a second planned to cover the resilience and stress-signature material. She has also previously co-authored a mental health resource with Dr. Amy Silva and contributed a chapter to a leadership book on the post-pandemic workplace.

Frequently Asked Questions

What is the DNA Performance Framework?

It's a coaching model developed by Alessandra Edwards that maps four personalised "signatures" (energy, stress, athletic, and diet) to help clients build routines suited to their own genetics rather than generic wellness advice.

What are "energy signatures" and how many types are there?

Energy signatures describe how a person's energy rises and falls through the day. Three types discussed include the Supernova (bursts of high output followed by crashes), the Electric Star (sustained high output needing frequent short breaks), and the Shooting Star (sharper energy swings benefiting from regular small protein-rich meals).

Why do high-performing women experience unexplained exhaustion?

Alessandra points to exhaustion that persists despite adequate sleep, often paired with brain fog, as a sign of a deeper biochemical or hormonal pattern rather than simple tiredness or lack of willpower.

Can perimenopause really affect confidence at work?

Yes. Hormonal shifts during perimenopause, such as declining oestrogen, can lower serotonin and dopamine and slow metabolism, changes that can present as loss of confidence, motivation, or sense of self, particularly in demanding leadership roles.

How can genetics inform diet and exercise timing?

Genetics can influence factors like how quickly the body clears caffeine, which foods provide sustained energy, and which times of day are best suited for exercise, deep focus work, or rest, all of which the DNA Performance Framework maps individually.

Where can I learn more about Alessandra Edwards' work?

Alessandra shares practical tips through her website newsletter and is active on LinkedIn. She is not active on other social platforms, having stepped back from them to focus her energy on client work.

Conclusion

The throughline in Alessandra Edwards' work is that exhaustion, sleep disruption, and confidence loss in high performers usually aren't failures of discipline, they're signals worth listening to, often with a genetic or hormonal root that generic wellness advice was never built to address.

Her DNA Performance Framework offers a more personalised lens: understand your own operating manual first, then make small, deliberate changes rather than piling on more habits. For the business owners, executives, and thought leaders she works with, that shift alone tends to be the most relieving part of the process.

Work With Jane Anderson

Want to go deeper on building sustainable high performance as a leader or practice owner? Explore more conversations with experts like Alessandra, learn about coaching and mentoring support through 1:1 Coaching, or listen to the full conversation in the Podcast.

 

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Most of the guests interviewed are current or alumni members of the Women With Influence community. Click here to find out more

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